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Escin

Rating: Best
Benefits: Anti-Aging/Longevity, Soothing
Categories: Antioxidant, Plant Extracts

Escin at a Glance

  • Main saponin of the horse chestnut tree
  • Exhibits antioxidant properties
  • Could also have topical anti-inflammatory properties
  • Also known as aescin

Escin Description

Escin, also called aescin, is the main saponin (a type of carbohydrate) of _Aesculus hippocastanum_, or horse chestnut, a tree native to parts of Europe, Asia, the Middle East, and North America.

Like most plant extracts, it exhibits antioxidant properties. Of most interest though to researchers, however, is its potential to mitigate factors that can lead to inflammation. Though this research is primarily linked to oral use, there’s exciting potential for it to have the same benefits when applied topically as well.


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Escin References

Pharmacology, Toxicology & Pathology, December 2021, ePublication
Journal of Basic and Clinical Physiology and Pharmacology, July 2020, ePublication
Drug Development Research, November 2019, pages 921-932
Drug Design, Development and Therapy, September 2019, pages 3425–3437
Chinese Journal of Natural Medicines, February 2018, pages 105-112