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Oligopeptide-3

Rating: Good
Benefits: Anti-Aging/Longevity, Hydration
Categories: Peptides

Oligopeptide-3 at a Glance

  • Peptide made up of several amino acids
  • Manufacturers claim it boosts skin’s resilience
  • Has hydrating properties
  • Known by the trade name Creapep ®

Oligopeptide-3 Description

Oligopeptide-3 is a synthetic (lab-engineered) peptide made up of the amino acids alanine, lysine, phenylalanine, and tridecapeptide with leucine.

Manufacturers of oligopeptide-3, also known by the trade name Creapep ®, claim it binds with skin cell receptors to trigger increases of elastin, hyaluronic acid, and factors that increase skin resilience to fight visible signs of aging.

While there isn’t yet a breadth of independent, peer-reviewed research backing some of these claims, peptides are hydrating and skin conditioning ingredients that do help improve the look and feel of skin.

The recommended use level of oligopeptide-3 in skin care products is 0.01–0.1%, which speaks to the potency of this peptide and its affinity for skin.
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Oligopeptide-3 References

ULProspector, Website, Accessed August 2025
SpecialChem, Website, Accessed August 2025