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Peptides

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Category
Skin Concern
Skin Type
Showing 1 - 21 of 23 products
Showing 1 - 21 of 23 products
New
PLUMP + FIRM
Pro-Collagen Peptide Gloss Balm
$35.00
$35.00
121
Best Seller
Boost C15 Super Booster 20ML - Paula's Choice Singapore
BRIGHTEN UP
C15 Super Booster
$79.00
$79.00
390
Best Seller
Pro-Collagen Peptide Plumping Moisturizer 50ml - Paula's Choice Singapore
PLUMP + FIRM
Pro-Collagen Peptide Plumping Moisturizer
from $28.00
$69.00
287
Best Seller
Boost Pro-Collagen Multi-Peptide Booster 20ML - Paula's Choice Singapore
PLUMP + FIRM
Pro-Collagen Multi-Peptide Booster
from $28.00
$88.00
119
New
PLUMP + FIRM
Pro-Collagen Peptide Firming Eye Serum
from $24.00
$59.00
230
Sold Out
Best Seller
Clinical 1% Retinol Treatment 30ML - Paula's Choice Singapore
YOUTH EXTENDING
1% Retinol Treatment
from $24.00
$98.00
159
Best Seller
Clear Oil-Free Moisturizer 60ML - Paula's Choice Singapore
CLEAR
Oil-Free Moisturizer
from $20.00
$56.00
116
Resist Weightless Advanced Repairing Toner 118ML - Paula's Choice Singapore
BARRIER BALANCING
Weightless Advanced Repairing Toner
$45.00
$45.00
96
Best Seller
Clinical 0.3% Retinol + 2% Bakuchiol Treatment 30ML - Paula's Choice Singapore
YOUTH EXTENDING
0.3% Retinol + 2% Bakuchiol Treatment
from $24.00
$98.00
89
Sold Out
Award Winner
Boost 1% Retinol Booster 15ML - Paula's Choice Singapore
YOUTH EXTENDING
1% Retinol Booster
$79.00
$79.00
75
Water Infusing Electrolyte Moisturizer 50ML - Paula's Choice Singapore
PLUMP + FIRM
Water Infusing Electrolyte Moisturizer
from $25.00
$62.00
96
Resist Super Antioxidant Concentrate Serum with Vitamin C 30ML - Paula's Choice Singapore
YOUTH EXTENDING
Super Antioxidant Concentrate Serum with Vitamin C
from $20.00
$72.00
80
Best Seller
Resist Anti-Aging Eye Gel 15ML - Paula's Choice Singapore
Resist
Anti-Aging Eye Gel
from $25.00
$60.00
76
Sold Out
Clinical Ceramide Enriched Firming Eye Cream 15ML - Paula's Choice Singapore
YOUTH EXTENDING
Ceramide-Enriched Firming Eye Cream
from $34.00
$75.00
43
Resist Intensive Repair Cream with Retinol 50ML - Paula's Choice Singapore
YOUTH EXTENDING
Intensive Repair Cream with Retinol
$64.00
$64.00
59
Resist Daily Smoothing Treatment 5% AHA 50ML - Paula's Choice Singapore
SKIN PERFECTING
Daily Smoothing Treatment 5% AHA
from $22.00
$58.00
57
Skin Recovery Replenishing Moisturizer 60ML - Paula's Choice Singapore
YOUTH EXTENDING
Replenishing Moisturizer
$59.00
$59.00
31
Defense Essential Glow Moisturizer SPF 30 60ML - Paula's Choice Singapore
SKIN SHIELD+
Essential Glow Moisturizer SPF 30
from $22.00
$58.00
34
Resist Anti-Aging Eye Cream 15ML - Paula's Choice Singapore
Resist
Anti-Aging Eye Cream
from $24.00
$59.00
42
Resist Advanced Smoothing Treatment 10% AHA 30ML - Paula's Choice Singapore
SKIN PERFECTING
Advanced Smoothing Treatment 10% AHA
$62.00
$62.00
33
Boost Hyaluronic Acid + Peptide Lip Booster 10ML - Paula's Choice Singapore
PLUMP + FIRM
Hyaluronic Acid + Peptide Lip Booster
$50.00
$50.00
25

Peptides Skincare

Fine lines are deepening. Skin that has lost its bounce. A complexion that looks tired even when you are not. 

These are the visible signs of collagen slowing down, a process that begins in your mid-twenties and continues steadily from there.

Peptides are one of the most well-researched ways to address it. Short chains of amino acids signal the skin to produce more collagen and elastin, the proteins responsible for firmness, elasticity, and the kind of skin that holds its shape.

Every Paula's Choice peptide formula is fragrance-free, research-backed, and formulated with efficacious levels of peptides that genuinely support visible skin improvement over time. 

No fluff. No fragrance. Just ingredients that do more than sound good.

Visible Signs Peptides Address

If any of these describe what you are seeing in the mirror, peptides are a relevant addition to your routine:

  • Skin that feels less firm or looks less defined than it used to

  • Fine lines around the eyes, mouth, or forehead that were not there a few years ago

  • Cheeks or jaw that look slightly looser or less lifted

  • Skin that has lost its bounce and does not spring back the way it once did

  • A complexion that looks flat or deflated, even when you are well-rested

  • Wrinkles that have deepened despite a consistent skincare routine

These are all signs that collagen and elastin, the proteins that keep skin firm and elastic, have begun to slow down. 

That is not a skin problem. It is a biological process. But it is one that research-backed ingredients can visibly support.

What Are Peptides, and What Do They Actually Do?

Collagen is the protein that keeps skin firm and lifted. From your mid-twenties, the body produces less of it each year. UV damage accelerates that process. 

The visible result is skin that looks less defined, less supported, and less elastic over time.

Peptides work by sending a signal. 

When collagen breaks down, it releases small fragments that the skin reads as a prompt to produce more. Topical peptides mimic that prompt, encouraging the skin to rebuild more actively than it would on its own.

The result, with consistent use:

  • Visibly firmer-looking skin

  • Reduced appearance of fine lines and wrinkles

  • Improved elasticity, skin that holds its shape better

  • A stronger skin barrier and better moisture retention

  • Smoother, more even-looking texture overall

Peptides are not a one-application fix. Results build over weeks. Formulation quality and daily consistency matter more than any single application.

Why Peptides Matter Particularly in Singapore

Singapore's consistently high UV exposure can accelerate collagen breakdown and premature skin aging. UV Index readings commonly range from 6 to 9, with occasional spikes above 11, reaching levels classified as very high to extreme.

For many people in Singapore, visible signs of skin aging, fine lines, loss of firmness, and uneven tone appear earlier than they would in lower-UV climates.

There are two additional factors specific to Singaporean life that peptides help address:

1. Air-conditioned dehydration. 

Most people in Singapore move daily between outdoor heat and humidity and heavily air-conditioned interiors. That repeated shift draws moisture out of the skin's surface layers. 

A weakened moisture barrier makes the visible signs of aging appear more pronounced , fine lines look deeper, and skin looks less plump. 

Peptides support barrier function alongside collagen, which helps skin hold onto hydration more effectively.

2. Pigmentation that is slower to recover. 

Post-sun discoloration and post-inflammatory marks tend to fade more slowly in skin that has been chronically UV-exposed. 

While targeted brightening ingredients like vitamin C and AHA exfoliants address this more directly, consistent peptide use supports the skin renewal process that underpins all visible improvement over time.

Peptides work best in Singapore as part of a consistent morning and evening routine, paired with daily SPF, which remains the single most effective way to slow UV-driven collagen loss in the first place.

Paula's Choice Peptide Products — Shop by Skin Concern

What You Are Seeing

Recommended Product

Format & Why It Works

Skin that looks less firm and feels less resilient than it used to

Pro-Collagen Peptide Plumping Moisturizer

Lightweight gel-cream leave-on moisturizer. Delivers 24-hour hydration and visible plumping with 3X Pro-Collagen Peptides. Absorbs without heaviness and layers comfortably under makeup in Singapore’s humidity.

Lips that look thinner, drier, or more lined than they used to be

Pro-Collagen Peptide Gloss Balm

Leave-on lip treatment with a glossy, non-sticky finish. Clinically proven to visibly plump, smooth, and nourish lips with 3X Pro-Collagen Peptides while delivering long-lasting hydration for everyday wear. Available in sheer pink and deep plum tints

Puffy, tired-looking eyes, especially in the morning

Anti-Aging Eye Gel

Lightweight leave-on gel eye treatment with a cooling applicator that helps refresh and visibly de-puff the eye area. Peptides, hyaluronic acid, and licorice help hydrate, smooth fine lines, and reduce signs of fatigue. Well-suited to humid weather.

Fine lines and early wrinkles, want to target peptides more intensively

Pro-Collagen Multi-Peptide Booster

Concentrated leave-on peptide booster with a silky, lightweight texture. Can be used alone or mixed into a serum or moisturizer for added peptide support. Suited to those who want more targeted firming and wrinkle support without adding a heavier product layer.

Sagging or crepey skin alongside rough texture, visible pores, or deeper wrinkles

0.3% Retinol + 2% Bakuchiol Treatment

Leave-on treatment combining retinol, bakuchiol, and peptides. Targets loss of firmness, rough texture, enlarged pores, uneven tone, and wrinkles at the same time. 

Fine lines, dryness, and dark circles around the eyes

Anti-Aging Eye Cream

Rich balm-like eye cream that delivers long-lasting hydration while helping soften fine lines, dryness, and the appearance of under-eye shadows. Suitable for all skin types

One Ingredient, Different Jobs

Not all peptides do the same thing , which is why two products can both list peptides and perform very differently.

The most common type used in anti-aging skincare sends a signal to skin cells to produce more collagen. 

Think of them as the message that the skin sends to itself when collagen breaks down. Topical peptides replicate that message.

Other peptide types help deliver supportive minerals deeper into the skin or work specifically on elastin to improve the skin's ability to snap back into shape.

What matters practically: the peptides in Paula's Choice formulas are at efficacious levels, meaning enough to actually reach the skin and do the job, not just enough to appear on an ingredient label. 

That distinction is not always visible on packaging, but it is the difference between a product that changes how your skin looks over time and one that does not.

How to Use Peptides in Your Skincare Routine

Application order:

  1. Cleanse with a gentle water-soluble cleanser.

  2. Apply any water-based leave-on exfoliant if you use one (AHA or BHA); do this before peptides.

  3. Apply peptide serum or booster to clean skin.

  4. Follow with moisturizer, or use a peptide moisturizer as your final hydration step.

  5. For the eye area, apply peptide eye serum, cream, or gel after your moisturizer.

  6. In the morning, finish with broad-spectrum SPF 30 or greater.

How often:

Peptide serums and moisturizers can be used twice daily, morning and evening, for most skin types. They are well-tolerated and do not require a build-up period, the way retinol or AHA exfoliants do.

When you will notice results:

Skin texture and hydration improvements are often noticeable within 2 to 4 weeks. More meaningful changes to firmness, fine lines, and elasticity develop over 8 to 12 weeks of consistent use.

What to Pair With Peptides, and What to Approach With Care


Ingredient / Product

How It Works With Peptides

Best Way to Use Together

Hyaluronic Acid

Helps hydrate the skin while peptides support collagen and firmness underneath.

Can be used together in the same routine.

Niacinamide

Supports the skin barrier, uneven tone, and overall skin strength alongside peptides.

Apply before or after your peptide serum.

Ceramides

Helps strengthen and protect the skin barrier.

Works well in moisturizers used with peptides.

Retinol

Retinol boosts skin renewal while peptides support collagen production.

Use peptides in the morning and retinol at night for the best comfort.

Vitamin C

Helps brighten and protect skin while peptides support repair and firmness.

Use vitamin C in the morning; peptides can be used in the morning and evening.

Sunscreen

Protects collagen from UV damage while peptides help support repair.

Use sunscreen every morning, especially in Singapore’s strong UV conditions.

Copper Peptides + strong acids (AHA/BHA)

May become less effective when layered directly with strong low-pH exfoliants.

Use at different times or wait until exfoliants are fully absorbed before applying.

Multiple active ingredients together

Too many strong actives at once can overwhelm the skin.

Split ingredients between morning and evening routines when needed.

Peptides vs Retinol — Which One Does Your Skin Need?

Both address visible signs of aging. They work differently, and for many people in Singapore, both have a role.

Factor

Peptides

Retinol

Primary function

Signals the skin to produce more collagen and elastin

Speeds up cell turnover; helps reduce fine lines and wrinkles

Visible results

Firmer, more elastic skin; smoother texture

Visibly smoother, refined skin; reduced fine lines

Suitable for sensitive skin

Yes, well-tolerated by most skin types

Requires slow introduction; can cause initial dryness

Can be used together

Yes

Yes, on alternating evenings, or in the same formula

Time to visible results

4 to 8 weeks

4 to 12 weeks

Singapore suitability

Year-round, including sensitive or reactive skin

Year-round, when introduced gradually


If your skin is sensitive or you are new to anti-aging actives, start with peptides. They deliver visible results without requiring a cautious introduction period. 

If your main concern is fine lines, pore size, or more advanced signs of aging, retinol remains one of the most evidence-backed tools available , and peptides support its effect by reinforcing collagen alongside retinol's cell-turnover action.

Sunscreen reminder: Peptides support collagen repair, but they do not protect against UV damage. UV radiation is the fastest driver of collagen degradation. Always apply broad-spectrum sunscreen rated SPF 30 or greater every morning, regardless of whether you are indoors or out.


Frequently Asked Questions About Peptide Skincare Products

What do peptides do for your skin?

They signal the skin to produce more collagen and elastin, the proteins that keep skin firm and elastic. With consistent use, peptides visibly improve firmness, reduce the appearance of fine lines, strengthen the barrier, and help skin hold moisture.

What not to mix with peptides?

Peptides are compatible with most skincare ingredients. The main caution is copper peptides alongside low-pH acids (AHA or BHA). If your routine includes both, apply them in sequence with absorption time in between, or split them across morning and evening routines.

Which is better, retinol or peptides?

Neither is universally better. Retinol promotes cell turnover and is one of the most studied anti-aging ingredients available. Peptides support firmness and barrier function and are gentler on skin that cannot yet tolerate retinol. Many people use both retinol in the evening and peptides in the morning and evening.

Can I use peptides with retinol?

Yes. The 0.3% Retinol + 2% Bakuchiol Treatment already combines both in one formula. If used separately, apply retinol in the evening and peptides morning and evening, or both in the evening once your skin tolerates retinol well.

How do you know if peptides are working?

Look for gradual improvements in skin bounce, hydration, smoothness, and how supported the skin appears overall. Visible firming and softening of fine lines typically develop over several weeks of consistent use.

Where do peptides go in a skincare routine?

After cleansing and any leave-on exfoliant (AHA or BHA), apply before moisturizer.

How often should I apply peptides?

Twice daily, morning and evening, for most people. Unlike retinol or AHA exfoliants, peptides do not require a slow introduction and can be used from day one.

How quickly do peptides work?

Hydration and texture improvements are often noticeable within 2 to 4 weeks. Visible firming and reduction in fine lines typically develop over 8 to 12 weeks of consistent daily use.

Are peptides and collagen the same?

No. Collagen is the protein that keeps skin firm. Peptides are what signal the skin to produce more of it. Topical collagen molecules are too large to penetrate the skin; topical peptides are not. That is why peptide formulas are more effective at supporting firmness than topical collagen products.