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How is this retinoid product different from the following retinoid products?
While the RESIST Triple Active Total Repair Serum and CLINICAL 1% Retinol Treatment are similar to CLINICAL Pro Retinaldehyde Retinoid Treatment in that they can help to visibly improve sun damage, wrinkles and loss of firmness, each formula is a different strength, and each brings something unique to the table.
The RESIST Triple Active Total Repair Serum is a lightweight, milky serum that uses a combination of retinyl propionate and hexylresorcinol along with niacinamide to target moderate signs of aging along with concerns around discoloration from UV damage and barrier impairment. It’s considered a medium-strength retinol that’s ideal for those comfortable with retinol use.
The CLINICAL 1% Retinol Treatment is a lightweight cream that uses concentrated pure retinol to target moderate to stubborn signs of aging including etched lines, deep wrinkles and widespread tone/texture changes due to sun damage. It’s considered a high-strength retinol that’s ideal for experienced retinol users seeking a more concentrated skin care solution.
The CLINICAL Pro Retinaldehyde Dual-Retinoid Treatment (global formula) is a fast-absorbing light lotion that uses a combination of retinaldehyde (aka retinal) and oleyl adapalenate (aka adapinoid) to target multiple signs of aging plus rough, bumpy texture and blemish/pore-related concerns. It’s considered a pro-strength (yet gentle) option that’s ideal for experienced high-strength retinol users seeking prescription-level results. The variant version is essentially the same minus the Adapinoid®.
How does CLINICAL Pro Retinaldehyde Retinoid Treatment compare to our Peptide Booster for skin firming?
The retinoids in CLINICAL Pro Retinaldehyde Retinoid Treatment primarily encourage the skin to produce more of its primary collagens (1 & 3), resulting in overall firmer skin. For those whose primary concern is loss of firmness, a product like our Pro-Collagen Peptide Booster would be a great option as it takes a highly specialized approach to repairing and helping to strengthen skin’s underlying architecture and has a near-instant smoothing effect on expression lines.
For those with concerns around signs of aging, blemishes and loss of firmness, using both the CLINICAL PRO Retinaldehyde Retinoid Treatment and the Peptide Booster will offer enhanced results. These products may be applied at the same time, or you can opt to use one in the morning and the other as part of your evening skin care routine.
Are there any ingredients or products this treatment isn’t compatible with?
No, you can use retinoids with other ingredients and skin care products. As an example, you can use this treatment with AHA, BHA, vitamin C, niacinamide and more. However, consult your prescribing physician or healthcare provider if you’re currently using a prescription topical or oral retinoid product.
Is the retinoid in this formula encapsulated?
Yes. This next-gen retinoid formula uses calcium microparticles (calcium phosphate, ingredient name is hydroxyapatite) which acts as a protective shell for retinaldehyde, shielding from factors like light and air that can cause retinoid degradation. This controlled release mechanism also helps maintain stable levels of retinaldehyde in the skin, minimizing irritation and maximizing benefits.
Can I use the CLINICAL Pro Retinaldehyde Retinoid Treatment during the day?
Yes, the CLINICAL Pro Retinaldehyde Retinoid Treatment can be used day or night. When using it during the day make sure to use sunscreen as the last step in your skin care routine.
Do I need to use a moisturizer after using the CLINICAL Pro Retinaldehyde Retinoid Treatment?
The CLINICAL Pro Retinaldehyde Retinoid Treatment includes some humectants, but its light lotion texture will likely not be hydrating enough for most people on its own. Any of the Paula’s Choice moisturizers can be layered over the top to further soften and hydrate. This is also a great way to prevent any potential irritation and dryness from the potent retinoid in this formula. Those with very dry skin can try mixing this treatment with a few drops of our Moisture Renewal Oil Booster.
Is the CLINICAL Pro Retinaldehyde Retinoid Treatment for advanced retinoid users only?
No. While other options in our line may be more suitable for those new to retinoids, if your primary concerns include lines, wrinkles, rough/bumpy texture plus blemish and pore congestion issues, the CLINICAL Pro Retinaldehyde Retinoid Treatment is a great solution. Keep in mind that higher concentration retinoids can be irritating (for some) so it's important to start slowly, gradually increasing your usage over several weeks.
Will the CLINICAL Pro Retinaldehyde Retinoid Treatment cause purging?
While unlikely (not everyone experiences purging, and there's no way to predict who will), some may experience a short purge. This is because potent retinoids such as retinal (even if gentle) are like power up buttons for cellular turnover. This is great in the long run, but sometimes those trapped clogs and bumps hiding deeper in skin get pushed out faster, causing a temporary breakout.
Can the CLINICAL Pro Retinaldehyde Retinoid Treatment be used with any of our Boosters? If so, what’s the best method and frequency of application?
The CLINICAL Pro Retinaldehyde Retinoid Treatment can be used with all our boosters except the 1% Retinol Booster, since this combination is likely to be too much retinoid for most people. Apply boosters and retinoids from thinnest to thickest texture, then follow with moisturizer or sunscreen. If skin is more sensitive, consider using boosters in the morning and retinoid at night.
Can the CLINICAL Pro Retinaldehyde Retinoid Treatment be used with prescription retinoids or acne products?
Yes, however, before doing so, consult your pharmacist or healthcare provider and follow their advice. They may advise applying at separate times until skin adjusts. Discontinue use if any side effects appear.
Is the CLINICAL Pro Retinaldehyde Retinoid Treatment suitable for blemish-prone skin?
Yes, the formula is designed to be suitable for blemish-prone skin and particularly helpful for those struggling with signs of aging, texture, and breakouts. Adapalene also helps with rosacea and sensitivity issues.
Is the CLINICAL Pro Retinaldehyde Retinoid Treatment suitable for sensitive/rosacea skin?
Yes. Retinaldehyde is generally better tolerated than pure retinol, and the formula is fragrance-free with anti-irritants. Start by applying once or twice a week and increase slowly based on skin’s response.
Can I use the CLINICAL Pro Retinaldehyde Retinoid Treatment while pregnant or breastfeeding?
We recommend avoiding all vitamin A derivatives (including retinaldehyde) during pregnancy and breastfeeding. Always consult your doctor for personalized advice.
Can the CLINICAL Pro Retinaldehyde Retinoid Treatment be used around the eyes and/or lips?
Yes. Apply around the orbital bone (not on eyelids) and avoid direct contact with the lips. Be cautious of product migration and adjust use if sensitivity occurs.
Why does Paula’s Choice recommend starting slow with retinoids and working up to more frequent use?
Because retinoids are potent, a slow and gradual introduction helps minimize irritation and allows your skin to build tolerance. This ensures long-term benefits without discomfort.
When should retinoids be avoided?
Retinoids should be avoided during pregnancy (unless approved by your doctor), if you have sunburn, open wounds, certain skin conditions, or before/after laser or peel procedures.
What are the main signs of overusing retinoids?
Signs include excessive dryness, redness, flaking, peeling, irritation, and breakouts. To avoid this, start slow, don’t combine too many actives, and moisturize well.
Can teenagers use the CLINICAL Pro Retinaldehyde Retinoid Treatment?
While teens don’t need anti-aging products, they may benefit from retinoids for acne. Always consult a dermatologist for appropriate guidance for teen skin.